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Generating real-world evidence to eliminate tropical diseases across East Africa

Sameday Foundation bridges the gap between clinical care and implementation science. We leverage our community-based health networks and facility infrastructure in Eastern Uganda to evaluate, refine and scale life-saving health interventions.

Clinical anchor: Same Day Hospital, Mbale City.

Health workers in gloves prepare rapid diagnostic test kits at a community screening table
Clinical practice meets implementation science

From bedside to population-level solutions

Sameday Foundation operates at the intersection of direct healthcare delivery and health systems research. Our clinical facilities provide immediate care while serving as dynamic laboratories for implementation science.

Direct clinical delivery

  • Same Day Hospital Mbale
  • Community sickle cell screening
  • WASH & NTD prevention
  • Mobile health clinics

Implementation science

  • Reactive and active case detection
  • Molecular surveillance
  • Feasibility & bottleneck analysis
  • Community & behavioural insights
Implementation research pillars

Three pillars, one aim: interventions that work at scale

  • Pillar 1

    Malaria elimination & vector control

    Focus: evaluating the real-world feasibility of reactive case detection (RCD), GIS micro-stratification and targeted vaccine deployment across high-burden and border transmission zones.

    Key approach: integrating ultra-sensitive diagnostic protocols (LAMP / hsRDTs) into routine community outreach.

  • Pillar 2

    Neglected tropical diseases (NTDs) & WASH

    Focus: assessing integrated delivery models for schistosomiasis, soil-transmitted helminths (STHs), other priority NTDs and water infrastructure in rural communities.

    Key approach: combining clean-water hardware installation with community-led behavioural interventions.

  • Pillar 3

    Sickle cell disease & chronic care delivery

    Focus: identifying health-workforce and supply-chain bottlenecks in early infant diagnosis, hydroxyurea adherence and routine screening.

    Key approach: operationalising point-of-care diagnostics at primary healthcare facilities.

See the full research portfolio

A health worker with a stethoscope takes notes during a consultation
Research infrastructure & capacity

Same Day Hospital Mbale: our living laboratory

Located in Mbale, Eastern Uganda, Same Day Hospital is our primary clinical anchor, combining high-quality patient care with research capacity.

  • Good Clinical Laboratory Practice (GCLP) standards. Equipped for molecular diagnostics, sample biobanking and rapid testing.
  • Institutional governance. Ethical oversight through established IRB partnerships and data compliance aligned with national and international research standards.
  • Community engagement. Long-standing trust across district health teams (DHTs), village health teams (VHTs) and local leadership.

Inside Same Day Hospital Mbale

Funder & institutional partner alignment

Built for high-impact research collaborations

We collaborate with academic institutions, global health funders and national health authorities to translate evidence into policy.

  • Grant & consortium ready

    Experience in sub-grant management, rigorous financial reporting and protocol implementation.

  • Aligned with global priorities

    Our portfolio is designed around priorities of WHO/TDR, EDCTP, the Gates Foundation and Ministry of Health Uganda guidelines.

“Our research designs prioritise scalability, cost-effectiveness and seamless integration into national health systems from day one.”
Latest publications & technical resources

Evidence we are putting into the public domain

  • Technical report

    Feasibility of community-led reactive case detection for malaria in high-transmission border districts

    Request a copy
  • Policy brief

    Integrating point-of-care sickle cell screening into routine antenatal care in Eastern Uganda

    Request a copy
  • SOP manual

    Standard operating procedures for integrated WASH and NTD surveillance

    Request a copy

All publications & policy briefs

Accelerate evidence-based health solutions

Whether you are a donor, research institution or public health practitioner, explore how we can collaborate on implementation research in East Africa.

Partner with our research team

Support our clinical and research work